TB500 CAS 885340-08-9

Product details:

Product Name: TB500
Alias: Thymosin beta 4 acetate
CAS: 77591-33-4
MF: C212H350N56O78S
MW: 4963.49
Purity (HPLC): 95%min
Single Impurity (HPLC): 2.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): >= 80.0%
Water Content(Karl Fischer): <= 5.0%
Acetate Content (HPIC): <= 15.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Appearance: White powder
Specification: 2mg/vial,10vials/box

Description:

TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory agent.
One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein - Actin. Of the thousands of proteins present within human cells, actin represents roughly 10% of the total. It is thus a vital component of cell structure and movement.
Thymosin Beta-4 is a protein which consists of 43 amino acids and is encoded by the gene TMSB4X in the human body. It has been studies in numerous clinical trials. Research has shown that if the thymosin beta-4 peptide is used after a heart attack it can reactivate cardiac progenitor cells to repair damaged heart tissue.
Thymosin beta-4 is a very large molecule. In fact, it is so large that it cannot fit entirely into the receptor. Different sections of the molecule have different activities. TB-500 is the part of thymosin beta-4 hormone which promotes the most useful effects. For medical applications it is more practical to use the TB-500 instead of the entire Thymosin Beta-4 protein.

Thymosin beta 4 antibodies, antibody of Thymosin beta 4 manual high degree of specificity, immunohistochemica is use of this principle.First to pick up the tissues or cells of certain chemicals, as antigen or hapten, after immune animals get specificity of the antibodies, and the further of antibody to detect tissue or cell antigen of the same kind of material.Because of antigen and antibody of complex is a colorless, therefore also must use histochemistry method can display the antigen antibody combining site by its reach to the unknown antigen in the tissues or cells are qualitative, positioning and quantitative research.

TB-500 is an injectable peptide drug which can be used to promote healing, enhance range of motion in cases of injury, or reduce pain in case of injury by reducing inflammation. As yet its human use has been relatively uncommon and limited to individuals who like to experiment. Use in race horses has been more widespread, though it's not a prescription veterinary drug.

Application:

TB-500 is typically provided as lyophilized (freeze-dried) powder in vials of 2.0 mg. A convenient amount of sterile or bacteriostatic water will be added, such as 1.0 mL. In the most common dosing protocol, the entire vial is taken at one time. If taking the entire vial, the entire amount will be drawn into a syringe, typically an insulin syringe, and injected. Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference.

The most common dosing protocol is to take 2.0 or 2.5 mg of TB-500 twice per week for four to six weeks, and then reduce to a lower dosing rate such as once or twice per month for maintenance.

The body of knowledge is as yet limited with regard to TB-500 dosage. The above protocol may or may not be the most efficient, but it is the protocol with the most track record. It's entirely possible that as knowledge is gained, method of use will change. A reasonable possibility, for example, is to increase dosing frequency to 3x/week (which I have done personally to good effect), or to increase dosing to 4 or 5 mg twice per week. Before going to such a program, however, I recommend trying the standard protocol first.

If interested in animal uses, a typical dosing protocol for horses is a course of six 10 mg injections at 7-10 day intervals. For more intensive treatment, 20 mg is used weekly. For racing dogs, a typical protocol is a course of six 5 mg injections taken weekly.

COA:

Dosage and Usage:

Dosage depends on the purpose and severity of the injury / damage you are treating. People generally use between 4 to 8 mg of TB500 per week during the initial (loading) period of 4 to 6 weeks. Afterwards some opt to maintain the effects with a low 2 to 6 mg dose once every 2 weeks. The effects of TB-500 wear off within 2 - 3 weeks of injection.

TB500 is distributed as a lyophilized powder that should be kept out of the light and in a cool dry place. Reconstitution is done with bacteriostatic water or sodium chloride meant for injection. Doses range from 2-2.5mg twice weekly for 4-6 weeks (some user have reported success in dosing higher up to 8mg a week but how much more effective this is yet to be seen) . Beyond that, one to two monthly injections of 2-2.5mg of TB500 can be further utilized to maintain rapid recovery and flexibility in strained areas.
For optimal recovery, a combination of TB500 with MK-2866 (Ostarine) should be used. This combination allows the healing benefits of SARMS and peptides to delivery maximum results.

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